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Membrane deformation and scission by the HSV-1 nuclear egress complex

The nuclear egress complex (NEC) of herpesviruses such as HSV-1 is essential for the exit of nascent capsids from the cell nucleus. The NEC drives nuclear envelope vesiculation in cells, but the precise budding mechanism and the potential involvement of cellular proteins are unclear. Here we report...

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Detalles Bibliográficos
Autores principales: Bigalke, Janna M., Heuser, Thomas, Nicastro, Daniela, Heldwein, Ekaterina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105210/
https://www.ncbi.nlm.nih.gov/pubmed/24916797
http://dx.doi.org/10.1038/ncomms5131