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Membrane-Sculpting BAR Domains Generate Stable Lipid Microdomains

Bin-Amphiphysin-Rvs (BAR) domain proteins are central regulators of many cellular processes involving membrane dynamics. BAR domains sculpt phosphoinositide-rich membranes to generate membrane protrusions or invaginations. Here, we report that, in addition to regulating membrane geometry, BAR domain...

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Detalles Bibliográficos
Autores principales: Zhao, Hongxia, Michelot, Alphée, Koskela, Essi V., Tkach, Vadym, Stamou, Dimitrios, Drubin, David G., Lappalainen, Pekka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105227/
https://www.ncbi.nlm.nih.gov/pubmed/24055060
http://dx.doi.org/10.1016/j.celrep.2013.08.024