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Novel Benzoxazine-Based Aglycones Block Glucose Uptake In Vivo by Inhibiting Glycosidases

Glycoside hydrolases catalyze the selective hydrolysis of glycosidic bonds in oligosaccharides, polysaccharides, and their conjugates. β-glucosidases occur in all domains of living organisms and constitute a major group among glycoside hydrolases. On the other hand, the benzoxazinoids occur in livin...

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Detalles Bibliográficos
Autores principales: Bharathkumar, Hanumantharayappa, Sundaram, Mahalingam S., Jagadish, Swamy, Paricharak, Shardul, Hemshekhar, Mahadevappa, Mason, Daniel, Kemparaju, Kempaiah, Girish, Kesturu S., Basappa, Bender, Andreas, Rangappa, Kanchugarakoppal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105438/
https://www.ncbi.nlm.nih.gov/pubmed/25047583
http://dx.doi.org/10.1371/journal.pone.0102759