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A Peptide of Heparin Cofactor II Inhibits Endotoxin-Mediated Shock and Invasive Pseudomonas aeruginosa Infection

Sepsis and septic shock remain important medical problems with high mortality rates. Today's treatment is based mainly on using antibiotics to target the bacteria, without addressing the systemic inflammatory response, which is a major contributor to mortality in sepsis. Therefore, novel treatm...

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Detalles Bibliográficos
Autores principales: Kalle, Martina, Papareddy, Praveen, Kasetty, Gopinath, van der Plas, Mariena J. A., Mörgelin, Matthias, Malmsten, Martin, Schmidtchen, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105479/
https://www.ncbi.nlm.nih.gov/pubmed/25047075
http://dx.doi.org/10.1371/journal.pone.0102577