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A Peptide of Heparin Cofactor II Inhibits Endotoxin-Mediated Shock and Invasive Pseudomonas aeruginosa Infection
Sepsis and septic shock remain important medical problems with high mortality rates. Today's treatment is based mainly on using antibiotics to target the bacteria, without addressing the systemic inflammatory response, which is a major contributor to mortality in sepsis. Therefore, novel treatm...
Autores principales: | Kalle, Martina, Papareddy, Praveen, Kasetty, Gopinath, van der Plas, Mariena J. A., Mörgelin, Matthias, Malmsten, Martin, Schmidtchen, Artur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105479/ https://www.ncbi.nlm.nih.gov/pubmed/25047075 http://dx.doi.org/10.1371/journal.pone.0102577 |
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