Effects of a novel cyclic RGD peptidomimetic on cell proliferation, migration and angiogenic activity in human endothelial cells

BACKGROUND: Cyclic RGD peptidomimetics containing a bifunctional diketopiperazine scaffold are a novel class of high-affinity ligands for the integrins α(V)β(3) and α(V)β(5). Since integrins are a promising target for the modulation of normal and pathological angiogenesis, the present study aimed at...

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Detalles Bibliográficos
Autores principales: Fanelli, Roberto, Schembri, Laura, Piarulli, Umberto, Pinoli, Monica, Rasini, Emanuela, Paolillo, Mayra, Galiazzo, Marisa Carlotta, Cosentino, Marco, Marino, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105520/
https://www.ncbi.nlm.nih.gov/pubmed/25053992
http://dx.doi.org/10.1186/2045-824X-6-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105520/
https://www.ncbi.nlm.nih.gov/pubmed/25053992
http://dx.doi.org/10.1186/2045-824X-6-11

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