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Effects of a novel cyclic RGD peptidomimetic on cell proliferation, migration and angiogenic activity in human endothelial cells
BACKGROUND: Cyclic RGD peptidomimetics containing a bifunctional diketopiperazine scaffold are a novel class of high-affinity ligands for the integrins α(V)β(3) and α(V)β(5). Since integrins are a promising target for the modulation of normal and pathological angiogenesis, the present study aimed at...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105520/ https://www.ncbi.nlm.nih.gov/pubmed/25053992 http://dx.doi.org/10.1186/2045-824X-6-11 |