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A Subset of Circulating Blood Mycobacteria-Specific CD4 T Cells Can Predict the Time to Mycobacterium tuberculosis Sputum Culture Conversion

We investigated 18 HIV-negative patients with MDR-TB for M. tuberculosis (Mtb)- and PPD-specific CD4 T cell responses and followed them over 6 months of drug therapy. Twelve of these patients were sputum culture (SC) positive and six patients were SC negative upon enrollment. Our aim was to identify...

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Detalles Bibliográficos
Autores principales: Riou, Catherine, Gray, Clive M., Lugongolo, Masixole, Gwala, Thabisile, Kiravu, Agano, Deniso, Pamela, Stewart-Isherwood, Lynsey, Omar, Shaheed Vally, Grobusch, Martin P., Coetzee, Gerrit, Conradie, Francesca, Ismail, Nazir, Kaplan, Gilla, Fallows, Dorothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105550/
https://www.ncbi.nlm.nih.gov/pubmed/25048802
http://dx.doi.org/10.1371/journal.pone.0102178