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A Subset of Circulating Blood Mycobacteria-Specific CD4 T Cells Can Predict the Time to Mycobacterium tuberculosis Sputum Culture Conversion
We investigated 18 HIV-negative patients with MDR-TB for M. tuberculosis (Mtb)- and PPD-specific CD4 T cell responses and followed them over 6 months of drug therapy. Twelve of these patients were sputum culture (SC) positive and six patients were SC negative upon enrollment. Our aim was to identify...
Autores principales: | Riou, Catherine, Gray, Clive M., Lugongolo, Masixole, Gwala, Thabisile, Kiravu, Agano, Deniso, Pamela, Stewart-Isherwood, Lynsey, Omar, Shaheed Vally, Grobusch, Martin P., Coetzee, Gerrit, Conradie, Francesca, Ismail, Nazir, Kaplan, Gilla, Fallows, Dorothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105550/ https://www.ncbi.nlm.nih.gov/pubmed/25048802 http://dx.doi.org/10.1371/journal.pone.0102178 |
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