Aurora Kinases as Druggable Targets in Pediatric Leukemia: Heterogeneity in Target Modulation Activities and Cytotoxicity by Diverse Novel Therapeutic Agents

Leukemia is the most common pediatric malignancy, constituting more than 30% of all childhood cancers. Although cure rates have improved greatly, approximately one in five children relapse and poor survival rates post relapse remain a challenge. Given this, more effective and innovative therapeutic...

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Detalles Bibliográficos
Autores principales: Jayanthan, Aarthi, Ruan, Yibing, Truong, Tony H., Narendran, Aru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105567/
https://www.ncbi.nlm.nih.gov/pubmed/25048812
http://dx.doi.org/10.1371/journal.pone.0102741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105567/
https://www.ncbi.nlm.nih.gov/pubmed/25048812
http://dx.doi.org/10.1371/journal.pone.0102741

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