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Leptin Increases TNF-α Expression and Production through Phospholipase D1 in Raw 264.7 Cells

Epidemiological evidence suggests that obesity is associated with inflammation of the respiratory tract and the pathogenesis of asthma. The purpose of this study was to examine the role of phospholipase D1 (PLD1) in leptin-induced expression of the proinflammatory cytokine, tumor necrosis factor (TN...

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Detalles Bibliográficos
Autores principales: Lee, Se-Min, Choi, Hye-Jin, Oh, Cheong-Hae, Oh, Jae-Won, Han, Joong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105621/
https://www.ncbi.nlm.nih.gov/pubmed/25047119
http://dx.doi.org/10.1371/journal.pone.0102373