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Association of Single Nucleotide Polymorphisms in the Lens Epithelium-Derived Growth Factor (LEDGF/p75) with HIV-1 Infection Outcomes in Brazilian HIV-1+ Individuals

The lens epithelium-derived growth factor p75 (LEDGF/p75), coded by the PSIP1 gene, is an important host co-factor that interacts with HIV-1 integrase to target integration of viral cDNA into active genes. The aim of this study was to investigate the association of SNPs in the PSIP1 gene with diseas...

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Detalles Bibliográficos
Autores principales: Passaes, Caroline Pereira Bittencourt, Cardoso, Cynthia Chester, Caetano, Diogo Gama, Teixeira, Sylvia Lopes Maia, Guimarães, Monick Lindenmeyer, Campos, Dayse Pereira, Veloso, Valdilea Gonçalves, Babic, Dunja Z., Stevenson, Mario, Moraes, Milton Ozório, Morgado, Mariza Gonçalves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105638/
https://www.ncbi.nlm.nih.gov/pubmed/25047784
http://dx.doi.org/10.1371/journal.pone.0101780