Hyperinsulinemia Down-Regulates TLR4 Expression in the Mammalian Heart

Toll-like receptors (TLR) are key regulators of innate immune and inflammatory responses and their activation is linked to impaired glucose metabolism during metabolic disease. Determination of whether TLR4 signaling can be activated in the heart by insulin may shed light on the pathogenesis of diab...

Descripción completa

Detalles Bibliográficos
Autores principales: de Laat, Melody A., Gruntmeir, Kaylynn J., Pollitt, Christopher C., McGowan, Catherine M., Sillence, Martin N., Lacombe, Véronique A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105691/
https://www.ncbi.nlm.nih.gov/pubmed/25101057
http://dx.doi.org/10.3389/fendo.2014.00120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105691/
https://www.ncbi.nlm.nih.gov/pubmed/25101057
http://dx.doi.org/10.3389/fendo.2014.00120

Ejemplares similares