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Hyperinsulinemia Down-Regulates TLR4 Expression in the Mammalian Heart
Toll-like receptors (TLR) are key regulators of innate immune and inflammatory responses and their activation is linked to impaired glucose metabolism during metabolic disease. Determination of whether TLR4 signaling can be activated in the heart by insulin may shed light on the pathogenesis of diab...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105691/ https://www.ncbi.nlm.nih.gov/pubmed/25101057 http://dx.doi.org/10.3389/fendo.2014.00120 |