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CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype

Memory B cells (MBCs) are long-lived sources of rapid, isotype-switched secondary antibody-forming cell (AFC) responses. Whether MBCs homogeneously retain the ability to self-renew and terminally differentiate or if these functions are compartmentalized into MBC subsets has been unclear. It was prev...

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Detalles Bibliográficos
Autores principales: Zuccarino-Catania, Griselda V., Sadanand, Saheli, Weisel, Florian J., Tomayko, Mary M., Meng, Hailong, Kleinstein, Steven H., Good-Jacobson, Kim L., Shlomchik, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105703/
https://www.ncbi.nlm.nih.gov/pubmed/24880458
http://dx.doi.org/10.1038/ni.2914