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Genetic disruption of the core circadian clock impairs hippocampus-dependent memory

Perturbing the circadian system by electrolytically lesioning the suprachiasmatic nucleus (SCN) or varying the environmental light:dark schedule impairs memory, suggesting that memory depends on the circadian system. We used a genetic approach to evaluate the role of the molecular clock in memory. B...

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Detalles Bibliográficos
Autores principales: Wardlaw, Sarah M., Phan, Trongha X., Saraf, Amit, Chen, Xuanmao, Storm, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105720/
https://www.ncbi.nlm.nih.gov/pubmed/25034823
http://dx.doi.org/10.1101/lm.035451.114