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Pokeweed antiviral protein alters splicing of HIV-1 RNAs, resulting in reduced virus production

Processing of HIV-1 transcripts results in three populations in the cytoplasm of infected cells: full-length RNA, singly spliced, and multiply spliced RNAs. Rev, regulator of virion expression, is an essential regulatory protein of HIV-1 required for transporting unspliced and singly spliced viral t...

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Detalles Bibliográficos
Autores principales: Zhabokritsky, Alice, Mansouri, Sheila, Hudak, Katalin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105749/
https://www.ncbi.nlm.nih.gov/pubmed/24951553
http://dx.doi.org/10.1261/rna.043141.113