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Pokeweed antiviral protein alters splicing of HIV-1 RNAs, resulting in reduced virus production
Processing of HIV-1 transcripts results in three populations in the cytoplasm of infected cells: full-length RNA, singly spliced, and multiply spliced RNAs. Rev, regulator of virion expression, is an essential regulatory protein of HIV-1 required for transporting unspliced and singly spliced viral t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105749/ https://www.ncbi.nlm.nih.gov/pubmed/24951553 http://dx.doi.org/10.1261/rna.043141.113 |