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Characterization of two homologous 2′-O-methyltransferases showing different specificities for their tRNA substrates

The 2′-O-methylation of the nucleoside at position 32 of tRNA is found in organisms belonging to the three domains of life. Unrelated enzymes catalyzing this modification in Bacteria (TrmJ) and Eukarya (Trm7) have already been identified, but until now, no information is available for the archaeal e...

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Detalles Bibliográficos
Autores principales: Somme, Jonathan, Van Laer, Bart, Roovers, Martine, Steyaert, Jan, Versées, Wim, Droogmans, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105751/
https://www.ncbi.nlm.nih.gov/pubmed/24951554
http://dx.doi.org/10.1261/rna.044503.114