Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic disorder leading to end-stage renal failure in humans. In the PKD/Mhm(cy/+) rat model of ADPKD, the point mutation R823W in the sterile alpha motif (SAM) domain of the protein ANKS6 is responsible for disease...

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Detalles Bibliográficos
Autores principales: Leettola, Catherine N, Knight, Mary Jane, Cascio, Duilio, Hoffman, Sigrid, Bowie, James U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105859/
https://www.ncbi.nlm.nih.gov/pubmed/24998259
http://dx.doi.org/10.1186/1472-6807-14-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105859/
https://www.ncbi.nlm.nih.gov/pubmed/24998259
http://dx.doi.org/10.1186/1472-6807-14-17

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