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Exosomal shuttling of miR-126 in endothelial cells modulates adhesive and migratory abilities of chronic myelogenous leukemia cells

BACKGROUND: Recent findings indicate that exosomes released from cancer cells contain microRNAs (miRNAs) that may be delivered to cells of tumor microenvironment. RESULTS: To elucidate whether miRNAs secreted from chronic myelogenous leukemia cells (CML) are shuttled into endothelial cells thus affe...

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Detalles Bibliográficos
Autores principales: Taverna, Simona, Amodeo, Valeria, Saieva, Laura, Russo, Antonio, Giallombardo, Marco, De Leo, Giacomo, Alessandro, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105877/
https://www.ncbi.nlm.nih.gov/pubmed/25015105
http://dx.doi.org/10.1186/1476-4598-13-169