TGF-β Signaling Cooperates with AT Motif-Binding Factor-1 for Repression of the α-Fetoprotein Promoter

α-Fetoprotein (AFP) is known to be highly produced in fetal liver despite its barely detectable level in normal adult liver. On the other hand, hepatocellular carcinoma often shows high expression of AFP. Thus, AFP seems to be an oncogenic marker. In our present study, we investigated how TGF-β sign...

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Detalles Bibliográficos
Autores principales: Sakata, Nobuo, Kaneko, Satoshi, Ikeno, Souichi, Miura, Yutaka, Nakabayashi, Hidekazu, Dong, Xue-Yuan, Dong, Jin-Tang, Tamaoki, Taiki, Nakano, Naoko, Itoh, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106063/
https://www.ncbi.nlm.nih.gov/pubmed/25105025
http://dx.doi.org/10.1155/2014/970346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106063/
https://www.ncbi.nlm.nih.gov/pubmed/25105025
http://dx.doi.org/10.1155/2014/970346

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