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Isocudraxanthone K Induces Growth Inhibition and Apoptosis in Oral Cancer Cells via Hypoxia Inducible Factor-1α

Isocudraxanthone K (IK) is a novel, natural compound from a methanol extract of the root bark of Cudrania tricuspidata. It has not been shown previously that IK possessed antitumor activity. We investigated the antitumor effects and molecular mechanism of IK and related signal transduction pathway(s...

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Detalles Bibliográficos
Autores principales: Shin, Mee-Ran, Lee, Hwa-Jeong, Kang, Soo-Kyung, Auh, Q-Schick, Lee, Young-Man, Kim, Youn-Chul, Kim, Eun-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106071/
https://www.ncbi.nlm.nih.gov/pubmed/25105148
http://dx.doi.org/10.1155/2014/934691