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High sensitivity of cancer exome-based CD8 T cell neo-antigen identification

Recent data suggest that T-cell reactivity against tumor-specific neo-antigens may be central to the clinical efficacy of cancer immunotherapy. The development of personalized vaccines designed to boost T-cell reactivity against patient specific neo-antigens has been proposed largely on the basis of...

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Detalles Bibliográficos
Autores principales: van Buuren, Marit M, Calis, Jorg JA, Schumacher, Ton NM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106163/
https://www.ncbi.nlm.nih.gov/pubmed/25083320
http://dx.doi.org/10.4161/onci.28836