Attenuated Listeria monocytogenes reprograms M2-polarized tumor-associated macrophages in ovarian cancer leading to iNOS-mediated tumor cell lysis

A principal mechanism by which tumors evade immune-mediated elimination is through immunosuppression. Previous approaches to tumor immunotherapy have focused on modifying the immunosuppressive environment with immune checkpoint inhibitors, cytokine therapy, and other modalities with the intent to ge...

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Detalles Bibliográficos
Autores principales: Lizotte, Patrick H, Baird, Jason R, Stevens, Cynthia A, Lauer, Peter, Green, William R, Brockstedt, Dirk G, Fiering, Steven N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106169/
https://www.ncbi.nlm.nih.gov/pubmed/25083323
http://dx.doi.org/10.4161/onci.28926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106169/
https://www.ncbi.nlm.nih.gov/pubmed/25083323
http://dx.doi.org/10.4161/onci.28926

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