A deficiency of apoptosis inducing factor (AIF) in Harlequin mouse heart mitochondria paradoxically reduces ROS generation during ischemia-reperfusion

Background and Aims: AIF (apoptosis inducing factor) is a flavin and NADH containing protein located within mitochondria required for optimal function of the respiratory chain. AIF may function as an antioxidant within mitochondria, yet when released from mitochondria it activates caspase-independen...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Qun, Szczepanek, Karol, Hu, Ying, Thompson, Jeremy, Lesnefsky, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106194/
https://www.ncbi.nlm.nih.gov/pubmed/25101006
http://dx.doi.org/10.3389/fphys.2014.00271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106194/
https://www.ncbi.nlm.nih.gov/pubmed/25101006
http://dx.doi.org/10.3389/fphys.2014.00271

Ejemplares similares