Efficient Modulation of γ-Aminobutyric Acid Type A Receptors by Piperine Derivatives

[Image: see text] Piperine activates TRPV1 (transient receptor potential vanilloid type 1 receptor) receptors and modulates γ-aminobutyric acid type A receptors (GABA(A)R). We have synthesized a library of 76 piperine analogues and analyzed their effects on GABA(A)R by means of a two-microelectrode...

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Detalles Bibliográficos
Autores principales: Schöffmann, Angela, Wimmer, Laurin, Goldmann, Daria, Khom, Sophia, Hintersteiner, Juliane, Baburin, Igor, Schwarz, Thomas, Hintersteininger, Michael, Pakfeifer, Peter, Oufir, Mouhssin, Hamburger, Matthias, Erker, Thomas, Ecker, Gerhard F., Mihovilovic, Marko D., Hering, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106271/
https://www.ncbi.nlm.nih.gov/pubmed/24905252
http://dx.doi.org/10.1021/jm5002277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106271/
https://www.ncbi.nlm.nih.gov/pubmed/24905252
http://dx.doi.org/10.1021/jm5002277

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