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Human isoprenoid synthase enzymes as therapeutic targets

In the human body, the complex biochemical network known as the mevalonate pathway is responsible for the biosynthesis of all isoprenoids, which consists of a vast array of metabolites that are vital for proper cellular functions. Two key isoprenoids, farnesyl pyrophosphate (FPP) and geranylgeranyl...

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Detalles Bibliográficos
Autores principales: Park, Jaeok, Matralis, Alexios N., Berghuis, Albert M., Tsantrizos, Youla S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106277/
https://www.ncbi.nlm.nih.gov/pubmed/25101260
http://dx.doi.org/10.3389/fchem.2014.00050