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Human isoprenoid synthase enzymes as therapeutic targets
In the human body, the complex biochemical network known as the mevalonate pathway is responsible for the biosynthesis of all isoprenoids, which consists of a vast array of metabolites that are vital for proper cellular functions. Two key isoprenoids, farnesyl pyrophosphate (FPP) and geranylgeranyl...
Autores principales: | Park, Jaeok, Matralis, Alexios N., Berghuis, Albert M., Tsantrizos, Youla S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106277/ https://www.ncbi.nlm.nih.gov/pubmed/25101260 http://dx.doi.org/10.3389/fchem.2014.00050 |
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