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Prions: Generation and Spread Versus Neurotoxicity

Neurodegenerative diseases are characterized by the aggregation of misfolded proteins in the brain. Among these disorders are the prion diseases, which are transmissible, and in which the misfolded proteins (“prions”) are also the infectious agent. Increasingly, it appears that misfolded proteins in...

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Detalles Bibliográficos
Autores principales: Halliday, Mark, Radford, Helois, Mallucci, Giovanna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106307/
https://www.ncbi.nlm.nih.gov/pubmed/24860100
http://dx.doi.org/10.1074/jbc.R114.568477