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Siglec-E Promotes β2-Integrin-dependent NADPH Oxidase Activation to Suppress Neutrophil Recruitment to the Lung

Siglec-E is a sialic acid-binding Ig-like lectin expressed on murine myeloid cells. It has recently been shown to function as a negative regulator of β2-integrin-dependent neutrophil recruitment to the lung following exposure to lipopolysaccharide (LPS). Here, we demonstrate that siglec-E promoted n...

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Detalles Bibliográficos
Autores principales: McMillan, Sarah J., Sharma, Ritu S., Richards, Hannah E., Hegde, Vikas, Crocker, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106349/
https://www.ncbi.nlm.nih.gov/pubmed/24895121
http://dx.doi.org/10.1074/jbc.M114.574624