Codon-by-Codon Modulation of Translational Speed and Accuracy Via mRNA Folding

Rapid cell growth demands fast protein translational elongation to alleviate ribosome shortage. However, speedy elongation undermines translational accuracy because of a mechanistic tradeoff. Here we provide genomic evidence in budding yeast and mouse embryonic stem cells that the efficiency–accurac...

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Detalles Bibliográficos
Autores principales: Yang, Jian-Rong, Chen, Xiaoshu, Zhang, Jianzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106722/
https://www.ncbi.nlm.nih.gov/pubmed/25051069
http://dx.doi.org/10.1371/journal.pbio.1001910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106722/
https://www.ncbi.nlm.nih.gov/pubmed/25051069
http://dx.doi.org/10.1371/journal.pbio.1001910

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