Uncoupling between Inflammatory and Fibrotic Responses to Silica: Evidence from MyD88 Knockout Mice

The exact implication of innate immunity in granuloma formation and irreversible lung fibrosis remains to be determined. In this study, we examined the lung inflammatory and fibrotic responses to silica in MyD88-knockout (KO) mice. In comparison to wild-type (WT) mice, we found that MyD88-KO animals...

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Detalles Bibliográficos
Autores principales: Lo Re, Sandra, Yakoub, Yousof, Devosse, Raynal, Uwambayinema, Francine, Couillin, Isabelle, Ryffel, Bernard, Marbaix, Etienne, Lison, Dominique, Huaux, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106757/
https://www.ncbi.nlm.nih.gov/pubmed/25050810
http://dx.doi.org/10.1371/journal.pone.0099383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106757/
https://www.ncbi.nlm.nih.gov/pubmed/25050810
http://dx.doi.org/10.1371/journal.pone.0099383

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