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IGF-IR Signal Transduction Protein Content and Its Activation by IGF-I in Human Placentas: Relationship with Gestational Age and Birth Weight

INTRODUCTION: The human placenta expresses the IGF-I and IGF-IR proteins and their intracellular signal components (IRS-1, AKT and mTOR). The aim of this study was to assess the IGF-IR content and activation of downstream signaling molecules in placentas from newborns who were classified by gestatio...

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Detalles Bibliográficos
Autores principales: Iñiguez, Germán, Castro, Juan José, Garcia, Mirna, Kakarieka, Elena, Johnson, M. Cecilia, Cassorla, Fernando, Mericq, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106823/
https://www.ncbi.nlm.nih.gov/pubmed/25050889
http://dx.doi.org/10.1371/journal.pone.0102252