FRET-Assisted Determination of CLN3 Membrane Topology

Juvenile neuronal ceroid lipofuscinosis (JNCL) is caused by mutations in the CLN3 gene, which encodes for a putative lysosomal transmembrane protein with thus far undescribed structure and function. Here we investigate the membrane topology of human CLN3 protein with a combination of advanced molecu...

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Detalles Bibliográficos
Autores principales: Ratajczak, Ewa, Petcherski, Anton, Ramos-Moreno, Juliana, Ruonala, Mika O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106830/
https://www.ncbi.nlm.nih.gov/pubmed/25051496
http://dx.doi.org/10.1371/journal.pone.0102593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106830/
https://www.ncbi.nlm.nih.gov/pubmed/25051496
http://dx.doi.org/10.1371/journal.pone.0102593

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