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A Role for Na(+),K(+)-ATPase α1 in Regulating Rab27a Localisation on Melanosomes

The mechanism(s) by which Rab GTPases are specifically recruited to distinct intracellular membranes remains elusive. Here we used Rab27a localisation onto melanosomes as a model to investigate Rab targeting. We identified the α1 subunit of Na(+),K(+)-ATPase (ATP1a1) as a novel Rab27a interacting pr...

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Detalles Bibliográficos
Autores principales: Booth, Antonia E. G., Tarafder, Abul K., Hume, Alistair N., Recchi, Chiara, Seabra, Miguel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106853/
https://www.ncbi.nlm.nih.gov/pubmed/25051489
http://dx.doi.org/10.1371/journal.pone.0102851