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Rapid Rebound of the Treg Compartment in DEREG Mice Limits the Impact of Treg Depletion on Mycobacterial Burden, but Prevents Autoimmunity

The development of an effective vaccine against tuberculosis (Tb) represents one of the major medical challenges of this century. Mycobacterium bovis Bacille Calmette-Guerin (BCG), the only vaccine available at present, is mostly effective at preventing disseminated Tb in children, but shows variabl...

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Detalles Bibliográficos
Autores principales: Berod, Luciana, Stüve, Philipp, Varela, Filipa, Behrends, Jochen, Swallow, Maxine, Kruse, Friederike, Krull, Freyja, Ghorbani, Peyman, Mayer, Christian T., Hölscher, Christoph, Sparwasser, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106855/
https://www.ncbi.nlm.nih.gov/pubmed/25050936
http://dx.doi.org/10.1371/journal.pone.0102804