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CNN3 Regulates Trophoblast Invasion and Is Upregulated by Hypoxia in BeWo Cells

CNN3 is an ubiquitously expressed F-actin binding protein, shown to regulate trophoblast fusion and hence seems to play a role in the placentation process. In this study we demonstrate that CNN3 levels are upregulated under low oxygen conditions in the trophoblast cell line BeWo. Since hypoxia is di...

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Detalles Bibliográficos
Autores principales: Appel, Sarah, Ankerne, Janina, Appel, Jan, Oberthuer, Andre, Mallmann, Peter, Dötsch, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106885/
https://www.ncbi.nlm.nih.gov/pubmed/25050546
http://dx.doi.org/10.1371/journal.pone.0103216