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Histone Acetyltransferase p300 Mediates Histone Acetylation of PS1 and BACE1 in a Cellular Model of Alzheimer's Disease

Epigenetic modifications, particularly histone acetylation, have been implicated in Alzheimer's disease (AD). While previous studies have suggested that histone hypoacetylation may regulate the expression of genes associated with memory and learning in AD, little is known about histone regulati...

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Detalles Bibliográficos
Autores principales: Lu, Xi, Deng, Yushuang, Yu, Daohai, Cao, Huiming, Wang, Li, Liu, Li, Yu, Caijia, Zhang, Yuping, Guo, Xiuming, Yu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106886/
https://www.ncbi.nlm.nih.gov/pubmed/25051175
http://dx.doi.org/10.1371/journal.pone.0103067