Cargando…

Histone Acetyltransferase p300 Mediates Histone Acetylation of PS1 and BACE1 in a Cellular Model of Alzheimer's Disease

Epigenetic modifications, particularly histone acetylation, have been implicated in Alzheimer's disease (AD). While previous studies have suggested that histone hypoacetylation may regulate the expression of genes associated with memory and learning in AD, little is known about histone regulati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Xi, Deng, Yushuang, Yu, Daohai, Cao, Huiming, Wang, Li, Liu, Li, Yu, Caijia, Zhang, Yuping, Guo, Xiuming, Yu, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106886/ https://www.ncbi.nlm.nih.gov/pubmed/25051175 http://dx.doi.org/10.1371/journal.pone.0103067

Ejemplares similares

Histone Acetylation Modifiers in the Pathogenesis of Alzheimer’s Disease
por: Lu, Xi, et al.
Publicado: (2015)

Snail acetylation by histone acetyltransferase p300 in lung cancer
por: Chang, Rui, et al.
Publicado: (2017)

Structure of the p300 Histone Acetyltransferase Bound to Acetyl-Coenzyme A and Its Analogues
por: Maksimoska, Jasna, et al.
Publicado: (2014)

Investigation of the Acetylation Mechanism by GCN5 Histone Acetyltransferase
por: Jiang, Junfeng, et al.
Publicado: (2012)

The Role of p300 Histone Acetyltransferase in UV-Induced Histone Modifications and MMP-1 Gene Transcription
por: Kim, Min-Kyoung, et al.
Publicado: (2009)

Histone acetylation and histone acetyltransferases show significant alterations in human abdominal aortic aneurysm
por: Han, Yanshuo, et al.
Publicado: (2016)

Stepwise acetyltransferase association and histone acetylation at the Myod1 locus during myogenic differentiation
por: Hamed, Munerah, et al.
Publicado: (2013)

A single histone acetyltransferase from Tetrahymena macronuclei catalyzes deposition-related acetylation of free histones and transcription-related acetylation of nucleosomal histones
Publicado: (1987)

Histone Acetylation Level and Histone Acetyltransferase/Deacetylase Activity in Ejaculated Sperm from Normozoospermic Men
por: Kim, Jee Hyun, et al.
Publicado: (2014)

Characterization of the human mucin 5AC promoter and its regulation by the histone acetyltransferase P300
por: Xu, Shiyao, et al.
Publicado: (2019)

ERRATUM: Stepwise acetyltransferase association and histone acetylation at the Myod1 locus during myogenic differentiation
por: Hamed, Munerah, et al.
Publicado: (2014)

Camello, a novel family of Histone Acetyltransferases that acetylate histone H4 and is essential for zebrafish development
por: Karmodiya, Krishanpal, et al.
Publicado: (2014)

MOF as an evolutionarily conserved histone crotonyltransferase and transcriptional activation by histone acetyltransferase-deficient and crotonyltransferase-competent CBP/p300
por: Liu, Xiaoguang, et al.
Publicado: (2017)

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts
por: Chen, Guozhen, et al.
Publicado: (2009)

Acetyltransferase p300/CBP Associated Factor (PCAF) Regulates Crosstalk-Dependent Acetylation of Histone H3 by Distal Site Recognition
por: Kornacki, James R., et al.
Publicado: (2014)

Influenza A virus nucleoprotein is acetylated by histone acetyltransferases PCAF and GCN5
por: Hatakeyama, Dai, et al.
Publicado: (2018)

Epigenetic mechanisms to propagate histone acetylation by p300/CBP
por: Kikuchi, Masaki, et al.
Publicado: (2023)

And-1 is required for the stability of histone acetyltransferase Gcn5
por: Li, Yongming, et al.
Publicado: (2011)

Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents
por: Chen, Qingjuan, et al.
Publicado: (2022)

DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers
por: Li, Shanshan, et al.
Publicado: (2018)

Histone acetyltransferase NAA40 modulates acetyl-CoA levels and lipid synthesis
por: Charidemou, Evelina, et al.
Publicado: (2022)

Structure of Patt1 human proapoptotic histone acetyltransferase
por: Jędrzejewski, Roch Paweł, et al.
Publicado: (2013)

The Role of Histone Acetyltransferases and Histone Deacetylases in Photoreceptor Differentiation and Degeneration
por: Zhao, Meng, et al.
Publicado: (2020)

Histone Acetyltransferase GCN5 Affects Auxin Transport during Root Growth by Modulating Histone Acetylation and Gene Expression of PINs
por: Poulios, Stylianos, et al.
Publicado: (2022)

Is histone acetylation the most important physiological function for CBP and p300?
por: Bedford, David C., et al.
Publicado: (2012)

Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP
por: Tang, Yong, et al.
Publicado: (2008)

Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases
por: Michaelides, Michael R., et al.
Publicado: (2017)

Regulation of Myf5 Early Enhancer by Histone Acetyltransferase p300 during Stem Cell Differentiation
por: Francetic, Tanja, et al.
Publicado: (2012)

IRF5 is elevated in childhood-onset SLE and regulated by histone acetyltransferase and histone deacetylase inhibitors
por: Shu, Jin, et al.
Publicado: (2017)

A Histone Acetyltransferase p300 Inhibitor C646 Induces Cell Cycle Arrest and Apoptosis Selectively in AML1-ETO-Positive AML Cells
por: Gao, Xiao-ning, et al.
Publicado: (2013)

Therapeutic effects of selective p300 histone acetyl-transferase inhibitor on liver fibrosis
por: Kim, Hyunsik, et al.
Publicado: (2023)

CBP and p300 Histone Acetyltransferases Contribute to Homologous Recombination by Transcriptionally Activating the BRCA1 and RAD51 Genes
por: Ogiwara, Hideaki, et al.
Publicado: (2012)

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300 mutated lymphomas
por: Veazey, Kylee J., et al.
Publicado: (2020)

Histone acetyltransferase CBP-related H3K23 acetylation contributes to courtship learning in Drosophila
por: Li, Kai-Le, et al.
Publicado: (2018)

Effects of caffeine on cell viability and activity of histone deacetylase 1 and histone acetyltransferase in glioma cells
por: Chen, Jin-Cherng, et al.
Publicado: (2016)

Histone Acetyltransferases in Plant Development and Plasticity
por: Boycheva, Irina, et al.
Publicado: (2014)

Histone Acetyltransferases and Stem Cell Identity
por: He, Ruicen, et al.
Publicado: (2021)

Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling
por: Zheng, Xin, et al.
Publicado: (2013)

Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy
por: Haery, Leila, et al.
Publicado: (2015)

Histone Acetyltransferases as Regulators of Nonhistone Proteins: The Role of Interferon Regulatory Factor Acetylation on Gene Transcription
por: Masumi, Atsuko
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_b9hhnha3rbh7ea0a2kkso6jq8l