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The Effects of CAMPATH-1H on Cell Viability Do Not Correlate to the CD52 Density on the Cell Surface

Graft versus host disease (GvHD) is one of the main complications after hematological stem cell transplantation (HSCT). CAMPATH-1H is used in the pre-transplant conditioning regimen to effectively reduce GvHD by targeting CD52 antigens on T cells resulting in their depletion. Information regarding C...

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Detalles Bibliográficos
Autores principales: Lee, Fuiyee, Luevano, Martha, Veys, Paul, Yong, Kwee, Madrigal, Alejandro, Shaw, Bronwen E., Saudemont, Aurore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106894/
https://www.ncbi.nlm.nih.gov/pubmed/25050704
http://dx.doi.org/10.1371/journal.pone.0103254