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FMR1 Premutation Is an Uncommon Explanation for Premature Ovarian Failure in Han Chinese

BACKGROUND: In premature ovarian failure (POF), cessation of menstruation occurs before the expected age of menopause. Approximately 1% of women are affected. FMR1 premutation was reported to be responsible for up to 3.3%–6.7% of sporadic POF and 13% of familial cases in Caucasians, while the data w...

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Detalles Bibliográficos
Autores principales: Guo, Ting, Qin, Yingying, Jiao, Xue, Li, Guangyu, Simpson, Joe Leigh, Chen, Zi-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106897/
https://www.ncbi.nlm.nih.gov/pubmed/25050920
http://dx.doi.org/10.1371/journal.pone.0103316