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Pharmacology and clinical potential of vortioxetine in the treatment of major depressive disorder

Vortioxetine is a new multimodal action antidepressant with two types of action: serotonin transporter (SERT) blockade and a strong affinity for several serotoninergic receptors. It is an antagonist of the 5-HT3 and 5-HT7 receptors, a partial agonist of 5-HT1B, and an agonist of 5-HT1A. Its combined...

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Detalles Bibliográficos
Autores principales: Alvarez, Enric, Perez, Victor, Artigas, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106971/
https://www.ncbi.nlm.nih.gov/pubmed/25075188
http://dx.doi.org/10.2147/NDT.S41387