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Animal versus human oral drug bioavailability: Do they correlate?
Oral bioavailability is a key consideration in development of drug products, and the use of preclinical species in predicting bioavailability in human has long been debated. In order to clarify whether any correlation between human and animal bioavailability exist, an extensive analysis of the publi...
Autores principales: | Musther, Helen, Olivares-Morales, Andrés, Hatley, Oliver J.D., Liu, Bo, Rostami Hodjegan, Amin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science B.V
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107270/ https://www.ncbi.nlm.nih.gov/pubmed/23988844 http://dx.doi.org/10.1016/j.ejps.2013.08.018 |
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