Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice

Integrins play an important role during development, regulating cell differentiation, proliferation and survival. Here we show that knockdown of integrin subunits slows down the progression of hepatocellular carcinoma (HCC). Using nanoparticulate delivery of short interfering RNAs targeting β1 and α...

Descripción completa

Detalles Bibliográficos
Autores principales: Bogorad, Roman L, Yin, Hao, Zeigerer, Anja, Nonaka, Hidenori, Ruda, Vera, Zerial, Marino, Anderson, Daniel G, Koteliansky, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107318/
https://www.ncbi.nlm.nih.gov/pubmed/24844798
http://dx.doi.org/10.1038/ncomms4869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107318/
https://www.ncbi.nlm.nih.gov/pubmed/24844798
http://dx.doi.org/10.1038/ncomms4869

Ejemplares similares