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Notch signaling deficiency underlies age-dependent depletion of satellite cells in muscular dystrophy

Duchenne muscular dystrophy (DMD) is a devastating disease characterized by muscle wasting, loss of mobility and death in early adulthood. Satellite cells are muscle-resident stem cells responsible for the repair and regeneration of damaged muscles. One pathological feature of DMD is the progressive...

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Detalles Bibliográficos
Autores principales: Jiang, Chunhui, Wen, Yefei, Kuroda, Kazuki, Hannon, Kevin, Rudnicki, Michael A., Kuang, Shihuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107328/
https://www.ncbi.nlm.nih.gov/pubmed/24906372
http://dx.doi.org/10.1242/dmm.015917