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Cold temperature improves mobility and survival in Drosophila models of autosomal-dominant hereditary spastic paraplegia (AD-HSP)

Autosomal-dominant hereditary spastic paraplegia (AD-HSP) is a crippling neurodegenerative disease for which effective treatment or cure remains unknown. Victims experience progressive mobility loss due to degeneration of the longest axons in the spinal cord. Over half of AD-HSP cases arise from los...

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Detalles Bibliográficos
Autores principales: Baxter, Sally L., Allard, Denise E., Crowl, Christopher, Sherwood, Nina Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107329/
https://www.ncbi.nlm.nih.gov/pubmed/24906373
http://dx.doi.org/10.1242/dmm.013987