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Regulation of adenosine triphosphate-sensitive potassium channels suppresses the toxic effects of amyloid-beta peptide (25–35)

In this study, we treated PC12 cells with 0–20 μM amyloid-β peptide (25–35) for 24 hours to induce cytotoxicity, and found that 5–20 μM amyloid-β peptide (25–35) decreased PC12 cell viability, but adenosine triphosphate-sensitive potassium channel activator diazoxide suppressed the decrease in PC12...

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Detalles Bibliográficos
Autores principales: Kong, Min, Ba, Maowen, Liang, Hui, Shao, Peng, Yu, Tianxia, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107498/
https://www.ncbi.nlm.nih.gov/pubmed/25206372
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.01.007