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Chronic pre-treatment with memantine prevents amyloid-beta protein-mediated long-term potentiation disruption

Previous studies indicate that memantine, a low-affinity N-methyl-D-aspartate receptor antagonist, exerted acute protective effects against amyloid-β protein-induced neurotoxicity. In the present study, the chronic effects and mechanisms of memantine were investigated further using electrophysiologi...

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Detalles Bibliográficos
Autores principales: Li, Fushun, Chen, Xiaowei, Wang, Feiming, Xu, Shujun, Chang, Lan, Anwyl, Roger, Wang, Qinwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107499/
https://www.ncbi.nlm.nih.gov/pubmed/25206371
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.01.006