Cholesterol efflux is LXRα isoform-dependent in human macrophages

BACKGROUND: The nuclear receptor liver X receptor (LXR) has two isoforms: LXRα and LXRβ. LXR activation promotes cholesterol efflux in macrophages, but the relative importance of each LXR isoform in mediating cholesterol efflux remains elusive. METHODS: We evaluated the ability of different doses of...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, A Zhi Sha, Song, Zhi Yuan, Zhang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107624/
https://www.ncbi.nlm.nih.gov/pubmed/24996838
http://dx.doi.org/10.1186/1471-2261-14-80

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107624/
https://www.ncbi.nlm.nih.gov/pubmed/24996838
http://dx.doi.org/10.1186/1471-2261-14-80

Ejemplares similares