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Cholesterol efflux is LXRα isoform-dependent in human macrophages

BACKGROUND: The nuclear receptor liver X receptor (LXR) has two isoforms: LXRα and LXRβ. LXR activation promotes cholesterol efflux in macrophages, but the relative importance of each LXR isoform in mediating cholesterol efflux remains elusive. METHODS: We evaluated the ability of different doses of...

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Detalles Bibliográficos
Autores principales:	Ma, A Zhi Sha, Song, Zhi Yuan, Zhang, Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107624/ https://www.ncbi.nlm.nih.gov/pubmed/24996838 http://dx.doi.org/10.1186/1471-2261-14-80

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